Renal protection in immunoglobulin-A nephropathy

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Renal protection in immunoglobulin-A nephropathy.

Sir, I applaud the timely reminder by Nagy et al. [1] that good control of hypertension can do much to ameliorate the course of immunoglobulin-A nephropathy. There are some good antiproliferative agents coming along. Only I wish to point out that we have forgotten [2] the potential of anti-thromboxanes [3], which will surely be synergistic to angiotensin-converting enzyme or angiotensin-recepto...

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Renal transplantation in patients with primary immunoglobulin A nephropathy.

BACKGROUND Opinions on the clinical course and outcome of renal transplantation in patients with primary immunoglobulin A nephropathy (IgAN) have been controversial. METHODS We conducted a retrospective single-centre study on 542 kidney transplant recipients over the period 1984-2001. Long-term outcome and factors affecting recurrence in recipients with primary IgAN were analysed. RESULTS S...

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Management in immunoglobulin A nephropathy.

158 Hong Kong Med J Vol 15 No 2 # April 2009 # To the Editor— I read with interest the article by Cheung et al,1 who stated that there is still no effective treatment for immunoglobulin (Ig) A nephropathy. Some points need to be clarified however. Firstly, combination of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker is firstline therapy to preserve glomerular filtrati...

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Renal protection in IgA nephropathy requires strict blood pressure control.

Primary IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide [1,2]. Although IgAN was considered a benign condition for many years, we now know that many cases eventually progress to end-stage renal failure. According to recent reviews, the actuarial renal survival at 10 years is 80–85% in most studies. Moreover, 30–40% of affected individuals develop end-stage...

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Genetics of immunoglobulin A nephropathy.

INTRODUCTION Immunoglobulin (Ig) A nephropathy is the most common primary glomerulonephritis in the world and about 20% to 50% of patients with it develop progressive renal failure. There is considerable evidence to show that IgA nephropathy is influenced by genetic factors. The purpose of this review is to provide useful information concerning genetics of IgA nephropathy. METHODS AND RESULTS...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2005

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/gfi260